KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP3
All Species:
17.27
Human Site:
S338
Identified Species:
47.5
UniProt:
P08254
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08254
NP_002413.1
477
53977
S338
S
F
W
P
S
L
P
S
G
V
D
A
A
Y
E
Chimpanzee
Pan troglodytes
XP_508723
477
54030
S338
S
F
W
P
S
L
P
S
G
V
D
A
A
Y
E
Rhesus Macaque
Macaca mulatta
XP_001098400
477
54003
S338
S
F
W
P
S
L
P
S
G
V
D
A
T
Y
E
Dog
Lupus familis
XP_536598
470
53609
H339
R
I
D
A
A
Y
E
H
P
S
R
D
L
I
F
Cat
Felis silvestris
Mouse
Mus musculus
P28862
477
53827
S338
S
F
W
P
S
L
P
S
N
M
D
A
A
Y
E
Rat
Rattus norvegicus
P03957
475
53409
S336
S
F
W
P
S
L
P
S
N
M
D
A
A
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508976
476
54530
A341
F
L
P
T
G
I
D
A
A
Y
E
D
G
S
K
Chicken
Gallus gallus
XP_417175
496
56924
A357
T
F
W
P
S
L
V
A
G
F
D
A
A
Y
E
Frog
Xenopus laevis
O13065
467
52794
N336
N
I
D
A
A
Y
E
N
P
I
T
E
Q
I
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.7
50.7
N.A.
77.1
75
N.A.
56.5
53.6
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.4
67.7
N.A.
87
85.7
N.A.
72.3
66.5
66.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
86.6
86.6
N.A.
0
73.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
6.6
N.A.
93.3
93.3
N.A.
26.6
86.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
23
23
0
0
23
12
0
0
67
56
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
0
0
0
12
0
0
0
67
23
0
0
0
% D
% Glu:
0
0
0
0
0
0
23
0
0
0
12
12
0
0
67
% E
% Phe:
12
67
0
0
0
0
0
0
0
12
0
0
0
0
12
% F
% Gly:
0
0
0
0
12
0
0
0
45
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
23
0
0
0
12
0
0
0
12
0
0
0
23
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
12
0
0
0
67
0
0
0
0
0
0
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
12
23
0
0
0
0
0
0
% N
% Pro:
0
0
12
67
0
0
56
0
23
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
56
0
0
0
67
0
0
56
0
12
0
0
0
12
0
% S
% Thr:
12
0
0
12
0
0
0
0
0
0
12
0
12
0
0
% T
% Val:
0
0
0
0
0
0
12
0
0
34
0
0
0
0
0
% V
% Trp:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
23
0
0
0
12
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _